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In semaglutide-treated patients, the magnitude of benefit was directly related to the extent of weight loss

doi: 10.1007/978-3-030-74180-8_10

Nature Reviews Endocrinology@NatureRevEndoNew content online: The role of GLP1 receptor agonists in adult-onset type 1 diabetes mellitus bit.ly/4ePkiqY4:32 PM Jul 16, 20255.3KViews1246727

The results indicated that the solanezumab-treated group had greater cognitive decline on some measures relative to placebo, and that solanezumab treatment did not exert any beneficial effects on downstream biomarkers, whereas gantenerumab significantly reduced amyloid plaques, CSF total tau, and phospho-tau181 and attenuated increases in neurofilament light chain [53]