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Ho, Suleen S, et al

Preclinical studies have found that Ex-4 significantly upregulates Sirt3 expression in glioblastoma by activating the GLP-1R, which subsequently inhibits the growth, migration, invasion, and epithelial-mesenchymal transition of glioma cells [87]

Isopropyl -D-1-thiogalactopyranoside (Fermentas, Germany) was added till a final concentration of 1.0 mM in order to induce the bacterial cells