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It refers to the size and shape of sperm, which is a key indicator of sperm health evaluated during a semen analysis

For example, DAMPs such as HMGB1, S100A8/A9, cfDNA, and oxidized low-density lipoprotein (oxLDL) can interact with TLRs, leading to the activation of NF-B and IRF3 pathways through MyD88-dependent or -independent mechanisms

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