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Similarly, Mehdizadeh et al

chinensis can significantly inhibit the streptomycin-induced accumulation of TG and the expression of ERS markers in HepG2 cells and mouse liver ( The multi-target therapeutic effects of SCF against MASLD are mediated through diverse molecular mechanisms (see Figure 2), which schematically illustrates the modulation of AMPK-dependent lipid metabolism, PPAR/ signaling pathways, Nrf2/HO-1-mediated antioxidant responses, and PI3K/Akt/mTOR-regulated autophagy, alongside the inhibition of SREBP-1c-driven lipogenesis and endoplasmic reticulum stress

An evident pigmentation of the exposed bed can be seen, in the hyponychium and the proximal nail fold (Hutchinson sign)

In the DSS colitis mouse model, BSFL oil treatment produced measurable protective effects on colon tissue integrity, with the metabolic fingerprint providing mechanistic context for the observed anti-inflammatory phenotype that would not have been accessible from cytokine assays or gene expression alone