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Several potential pathways could link DHEA-S with frailty

J Biol Chem 293(8):28772887 Csibi A, Lee G, Yoon SO et al (2014) The mTORC1/S6K1 pathway regulates glutamine metabolism through the eIF4B-dependent control of c-Myc translation

These data indicate that melatonin-dependent NRF2 activation and glutathione-mediated suppression of effector function are conserved between murine and human ILC2s