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Key signal pathways in tumor metastasis Tumor metastasis is the most important cause of the unoptimistic prognosis of melanoma patients

Its distinctive inactive-to-active conversion within the tumor microenvironment augments metabolic targeting and selectivity, which underscores its potential as a groundbreaking therapeutic strategy [186, 187]

Nano encapsulation has been applied to enhance bioavailability, preserve the integrity of bioactive ingredients, increase half-life of the bioactive ingredients, reduce toxicity and side effects, target delivery to specific sites as well as improve the absorption and efficacy of bioactive ingredients

Hauser TU, Skvortsova V, De Choudhury M, Koutsouleris N