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Sandlin et al., 2022)

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Furthermore, folic acid (the pharmaceutical form of folate) has been shown to improve the function of the layer of cells lining the blood vessels (Antoniades et al, 2006)

We also found that some differential metabolites like trans-cinnamate and sphingosine 1-phosphate was significantly correlated with IL-13, IP-10, IFN-, and Eotaxin ( Padj 0.05), such as 3-hydroxyphenylacetate and prostaglandin H2, were also significantly correlated with IL-12, MCP-1 and IL-7 among patients with MS ( Padj 0.05) ( Figure S6 )