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Gastrointestinal effects are the most common
doi: 10.3390/biom13010159 16 ColeAJDwightTGillAJDicksonKAZhuYClarksonAet al
Stefnsson E, Olafsdottir OB, Eliasdottir TS, et al
Plausible degradation pathways include: Serum aminopeptidases (cleaving from the N-terminus) Endopeptidases (internal bond cleavage) Hepatic uptake and degradation Renal clearance (though direct renal excretion of intact peptide of this size is typically limited) Whether BPC-157 generates active metabolites i.e., smaller peptide fragments that retain biological activity is not established in the public literature
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