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Intestinal contraction is modulated by smooth mus- cle cells which are innervated under acetylcholine releasing.30 Our result correlates with the study of Fehri et al30 which proved that GAincreasedintestinalperistalsissignificantlyatadoseof400mg/ kg.Inaddition,the studyshowedthatGAincreased contractionof guinea pig isolated ileum by acetylcholine stimulate.30 GAAEimproved gastric emptying rate especially withthe dose of 400 mg /kg
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After 21 days, BW increased by 2.6% 0.71% in V rats and was reduced in the other cohorts by 8.7% 0.91% (CS), 5.6% 0.50% (PF) or 9.0% 0.42% (WM) (all P 3 C)
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