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Glutathione protects mitochondria from oxidative damage, ensuring they function efficiently

4,6 The most clinically significant elements of mucosal involvement are the sequelae of mucosal ulceration that result in scarring and stricture, which affect several organ systemsnamely, the cornea, urethra, esophagus, and pulmonary tract

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In addition to this attack, which might be caused by homocysteinylation of the vascular wall proteins by homocysteine and/or its oxidized products (homocysteic acid, homocysteine sulfinic acid, and homocysteine thiolactone), in vitro and in vivo work suggests that reduced homocysteine can inhibit endothelial cell turn-over (Wang et al, 1997) and promote smooth muscle cell proliferation (Lubec et al, 1996b