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3.6.3 Mechanisms linking gut dysbiosis to PSCI 3.6.3.1 Neuroinflammation Gut dysbiosis and increased intestinal permeability following ischemic stroke (IS) have been linked to systemic endotoxemia and altered microbial metabolite signaling, potentially exacerbating neuroinflammation and injury (Zhang W

This action is possible due to their capacity to inhibit pathways that trigger oxidative stress, and the synthesis and release of cytokines and chemokines, which are proinflammatory chemicals