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Nitrous Oxide Use and Myeloneuropathy When someone suffers from vitamin B12 deficiency due to nitrous oxide misuse, they may develop myeloneuropathy

14 Upon application to the skin, DHA undergoes a Maillard reaction: the carbonyl group of DHA reacts with amino acids such as arginine, histidine, and lysine in the stratum corneum to produce brown-black chromophores, known as melanoidins, which provide a brown coloration (Figure 2)