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ClinicalTrials.gov: NCT04881760), participants receiving the highest dose of retatrutide demonstrated mean body weight reductions of approximately 24% over 48 weeks among the most significant weight-loss outcomes observed in pharmacological trials to date

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That average weight loss rose to more than 15% by week 48 on the heaviest dose of ecnoglutide, researchers reported in updated trial results presented Saturday at the American Diabetes Associations annual meeting in Chicago

Signals that should register as "touch" are being routed through pain pathways