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Discrimination index D2 = (Tnew - Tfamiliar) / (Tnew + Tfamiliar)

Laron, Z., Avitzur, Y

Choosing the Right Medication for Your Rheumatoid Arthritis Because there are now so many different medications available to treat rheumatoid arthritis, the decision about which medications to use depends on several factors, including: Disease severity Response to treatment Cost Side effects Other pre-existing conditions or medical problems Physical Therapy and Exercise Exercise is an important part of a treatment program

Food and Drug Administration PubMed PubMed No published multi year surveillance exists for adverse events, and current absence of large documented harm does not imply safety equivalence to approved therapeutics with rigorous post marketing data