Results Bone metabolism: Five preclinical studies found GLP-1 agonists enhanced osteoblastic differentiation and increased bone formation in osteoporotic and diabetic models
Investigators are developing models to predict the efficacy of DPP-4 inhibitors, GLP-1 RAs, SGLT-2 inhibitors, sulfonylureas, and thiazolidinediones to lower HbA1c levels using widely available clinical features (age, duration of diabetes, sex, baseline HbA1c, BMI, estimated glomerular filtration rate, HDL cholesterol, total cholesterol, and alanine aminotransferase) to facilitate therapy (14)
We'll also learn more about new uses for these drugs
1 Modeled plasma concentrations following a missed dose at steady state 5,6,b,c When a dose of ARISTADA is missed, administer the next injection of ARISTADA as soon as possible