10.3389/fphar.2020.00425 Summary Keywords acute kidney injury, chuan huang fang, chronic kidney disease, renal fibrosis, reduced glutathione, traditional Chinese medicine Citation Chen L, Ye Z, Wang D, Liu J, Wang Q, Wang C, Xu B and Gong X (2022) Chuan Huang Fang combining reduced glutathione in treating acute kidney injury (grades 12) on chronic kidney disease (stages 24): A multicenter randomized controlled clinical trial
In addition, NRF2 was reported to confer radioprotection to human lung fibroblasts through upregulating miR-140 expression, which is involved in the regulation of lung fibroblast self-renewal [94]
Although the primary function of mitochondria is to generate ATP as an energy molecule required for countless cell functions, a small fraction of electrons from the ETC are transferred directly to O 2 , resulting in the generation of the superoxide anion, which can give rise to other ROS as well as reactive nitrogen species (RNS)
Meng YL, Hu HT, Li HL, Guo CY, Luo JP, Yao QJ, et al