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The ongoing phase 3 REIMAGINE clinical trials, designed for T2D patients, utilize the same 16-week dosing escalation protocol, with a maximum dose of 2.4 mg/week for both cagrilintide and semaglutide [13, 14]

Once in a liquid state, the compound must be stored under refrigeration at 2C to 8C

GSSG can be recycled as GSH through GSH reductase in an NADPH-dependent manner ( 2+ to yield significantly reactive alkoxy radicals (L-O-) (Shen et al., 2020)

Therefore, further investigation into the role of NRF2 in psoriasis and the exploration of safe and effective NRF2 activators for psoriasis treatment are warranted