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Safety Considerations and Future Outlook As with all pharmacotherapy for obesity and T2D, establishing cardiovascular safety and demonstrating improvements in meaningful clinical outcomes will be essential, particularly as cardiovascular outcome trials have not yet been completed with multi-agonists (although data are expected soon for tirzepatide: SURPASS-CVOT [T2D] in 2025

A third argument for adopting edible organisms for GLP-1 delivery would be to increase global accessibility

Taurine also improved their ability to perform in the heat.[ref] In obese women, taurine (3g/day) plus exercise reduced adipocyte size and improved inflammatory markers.[ref] Anti-aging: In a placebo-controlled clinical trial, taurine (1.6g/day for 16 weeks) increased antioxidant levels in women in their 60s.[ref] Fat burning: A double-blind clinical trial showed that taurine (6g, 90 min

Carnitine has been also found to turn on anabolic signaling genes as well