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Annals of Internal Medicine , 178 (2), 199217

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Persistent hunger throughout the day, no change in food noise or cravings, and no weight loss after 4 or more weeks on a stable dose all suggest the dose is too low or absorption is insufficient

Ridker PM, Devalaraja M, Baeres FMM et al (2021) IL-6 inhibition with ziltivekimab in patients at high atherosclerotic risk (RESCUE): a double-blind, randomised, placebo-controlled, phase 2 trial