It was that knowledge of glucagon sequence, and its biologywhich actually was very critical for my discovery of GLP-1. Originally thought to be simply responsible for triggering insulin secretion by the pancreas, scientists soon discovered that the hormone also inhibits glucagon secretion by the pancreas and delays gastric emptying
Common GLP-1 receptor agonist medications include semaglutide drugs such as Ozempic, Wegovy, and Rybelsus, as well as tirzepatide medications including Mounjaro and Zepbound
Glucagon-like peptide-1 (GLP-1) receptor agonists are a class of medications with specific UK licences: some are approved for type 2 diabetes management (semaglutide [Ozempic], dulaglutide [Trulicity], liraglutide [Victoza]), while others are specifically licensed for weight management in adults with obesity or overweight with weight-related comorbidities (semaglutide [Wegovy], liraglutide [Saxenda])
For many people, these medications have produced significant health benefits, including improved blood sugar control and reduced risk factors for chronic disease