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Description

This is important for the health of the animal, as healthy blood is key to a healthy life

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Based on the observation that Keap1 functions as a homodimer, the heterozygous missense mutation generates three types of Keap1 dimers, i.e., wild-type homodimer, wild-type-mutant heterodimer, and mutant homodimer at a ratio of 1:2:1

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HIF1-alpha-mediated gene expression induced by vitamin B1 deficiency

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This can lead to disruptions in synaptic integrity and neural circuitry (Cirelli 2002

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