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Taken together, these data indicate that genomic DNA oxidation is substantially increased in plants grown in lunar regolith simulant, consistent with the transcriptional activation of an oxidative stress response ( Finally, since oxidative stress levels can affect organelle function ( cox1, rps4 , and atp1 ), chloroplasts ( psbA , clpP and ndhH ) ( RpoTp and RpoTm ) as a control