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The increased risk may relate to rapid weight loss, changes in gallbladder motility, or alterations in bile acid composition

GLP-1 therapy combined with adequate protein intake, resistance training, and attention to sleep and stress creates a strong foundation for metabolic improvement

The extension covers four new strengths: 1.5 mg, 4 mg, 9 mg and 25 mg for oral use

Conversely, studies have shown that both patients and healthcare professionals are reluctant to initiate GLP-1RAs [11, 12], despite the guideline recommendations and the health benefits of these therapies, particularly for patients in need of weight loss and those with low estimated glomerular filtration rate [1]