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However, serious adverse effects can occur, including pancreatitis (severe persistent abdominal pain), gallbladder disease, and acute kidney injury (typically related to dehydration from gastrointestinal symptoms)
A meta-analysis of 18 RCTs confirmed PRPs superiority over placebo and corticosteroid injections, highlighting long-term benefits in pain reduction and tendon healing (PMID: 32073993)
However, modern high-dose daily oral options are rapidly narrowing that gap, offering a highly effective daily pill alternative with improved absorption
"Lilly is advancing the most comprehensive pipeline of obesity medicines, with a commitment to deliver innovative treatments that reflect the diverse needs and preferences of people living with obesity
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