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Supplements like L-carnitine can only play a supporting role

In contrast to GSH synthesis, which occurs intracellularly, GSH degradation occurs exclusively in the extracellular space, and in particular, on the surface of cells that express the enzyme -glutamyl transpeptidase (also called -glutamyl transferase, GGT

The role of PYY as a satiety hormone has been debated, as several independent research groups did not reproduce the anorectic effect in humans reported in the original study by Batterham et al