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Before diving into the newer findings, it's important to understand what GLPs are, where they came from, and what they were originally designed to do

Gas Chromatography-Mass Spectrometry (GC-MS) : GC-MS is another powerful tool for acylcarnitine analysis, particularly for volatile or less polar acylcarnitine derivatives

for example, the use of metformin in patients with renal impairment is associated with an increased risk of lactic acidosis, which can be fatal [36]

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