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Beyond its classical role in calcium homeostasis, vitamin D exerts an influence on steroidogenesis (95), inflammation (100), and OS (101), positioning it as a critical modulator in the PCOS phenotype

Nevertheless, the study fails to clarify differences in serum PCS levels among PBC patients at different disease stages, uses non-human primary Kupffer cells in vitro , and does not evaluate the safety threshold for clinical PCS supplementation, which limits its therapeutic translation

JAMA 281 , 22172224 (1999)

Aspirated the bacterial liquid to collect the bacterial precipitate, and then washed it twice with 0.85% physiological saline