CrossRef The burden of overweight: Higher body mass index, but not vital exhaustion, is associated with higher DNA damage and lower DNA repair capacity Judy Fieres, Marvin Fischer, Christine Sauter, Maria Moreno-Villanueva, Alexander Brkle, Petra H
The available approaches focus on metabolic pathway modifiers (e.g., the Farnesoid X-receptor agonists obeticholic acid and cilofexor, the acetyl-CoA carboxylase inhibitor firsocostat, the PPAR agonist elafibranor) on the one hand, and agents with anti-inflammatory and/or antifibrotic action (e.g., the CCR2/5 inhibitor cenicriviroc and the ASK-1 inhibitor selonsertib) on the other
In present work, we aimed to demonstrate the potential effect of GLP-1R on chondrocytes and elucidate its underlying mechanisms
It plays a major role in vasodilation, protein synthesis, and immune support