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There are two main types of gallstones: Cholesterol stones (80% of cases): Formed when bile contains too much cholesterol Pigment stones (20% of cases): Formed when bile contains excess bilirubin Risk factors and symptoms Several factors increase your risk of developing gallstones: When gallstones cause symptoms, they typically include: Sharp pain in the upper right abdomen that may radiate to your back or shoulder Nausea or vomiting Fever or chills (if infection develops) Yellowing of skin and eyes (jaundice) if stones block the bile ducts Indigestion, bloating, or heartburn What is Wegovy