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They may also run tests to rule out conditions (such as a gluten intolerance) that have many of the same symptoms like: Food allergies Side effects from medications Infection Enzyme deficiencies Inflammatory bowel diseases Your doctor may also run the following tests as part of the diagnosis process : Flexible sigmoidoscopy or colonoscopy to see if you have blockage or inflammation in your intestines X-Rays Upper endoscopy Blood tests to check for anemia, thyroid problems, and infection Stool tests An organic acid test Tests to check your bowel muscles If symptoms associated with IBS occur weekly for 3 months or less often for at least six months and youve been cleared of other conditions, then your doctor will diagnose you with IBS