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A scientific review published in the National Library of Medicine in 2022 found that nose-to-brain delivery of therapeutic peptides is a non-invasive and fast-acting method that can effectively bypass the blood-brain barrier while minimizing systemic exposure

Bhirud D, Bhattacharya S, Raval H, Sangave PC, Gupta GL, Paraskar G et al (2025) Chitosan nanoparticles of imatinib mesylate coated with TPGS for the treatment of colon cancer, In-vivo & in-vitro studies

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