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Coord Chem Rev, 2022, 454: 214330 Wang Y, Yue C, Zhang M, et al

27 October 2015

2009 in PNAS (PMC2667044) showed stress suppressed preproglucagon (PPG) mRNA in rat NTS neurons within 30 minutes via a glucocorticoid-dependent mechanism

Asimismo, fue demostrado que la diferenciacin insulina-positiva de clulas epiteliales pancreticas (AR42J) por la activacin de GLP-1R es mediada por cambios en la expresin de factores de transcripcin smad2 y smad3 y que la accin depende de isoformas endgenas del factor transformante de crecimiento beta (21,22)