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This vaccine, called Lipo@HEV is the product of combining B16F10, 4T1 and CT26 (epithelial, breast and colon) tumor cell lines with the biocompatible and coadjuvant outer membrane vesicle from Akkermansia muciniphila (Akk-OMV) and loaded with gene therapy plasmid encoding PD-L1 binding domain in a trimeric form that acts as a trap

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Evidence from human myectomy samples that MYBPC3 mutations cause hypertrophic cardiomyopathy through haploinsufficiency