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This phenomenon is primarily mediated through pathways, including the mitochondrial pathway ( 2.4.1 Mitochondrial pathway The mitochondrial pathway functions as the primary executor of programmed cell death and acts as a signal integration hub in radiation-induced apoptosis

Angiotensin II may contribute to alveolar epithelial dysfunction through a variety of mechanisms, including via systemic effects on vascular tone and fluid retention as well as via localized effects such as promoting apoptosis of alveolar epithelial cells

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