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Choose Injection Sites With Adequate Subcutaneous Tissue Injection sites with minimal subcutaneous fat, such as the inner thigh, the lower abdomen in leaner individuals, or areas close to bony prominences, offer less tissue cushioning between the needle and sensory nerve endings

doi: 10.3389/fcell.2025.1698296 Received 03 September 2025 Revised 02 December 2025 Accepted 04 December 2025 Published 08 January 2026 Volume 13 - 2025 Edited by Dongxu Wang, Jiangsu University of Science and Technology, China Reviewed by Mohamed Taha Moutaoufik, Mohammed VI Polytechnic University, Morocco Sudipta Ashe, Minutia Inc., United States Updates Copyright 2026 Ruchko, Chernysheva, Sokolov, Starinnov, Sabirov and Vasiliev

Understanding your genetic predisposition allows PlexusDx to design a treatment plan that minimizes fatigue from the outset

Supplementary table S3 compares the characteristics of the target trials and the emulated trials using our observational datasets