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Figure 3 shows the prediction-corrected VPC plots, where most observed data fell within the 95% confidence interval (CI) generated by model simulations, showing that the final model had good forecasting ability

Key drugs facing patent cliffs during this period include Keytruda (pembrolizumab) starting around 2028, Eliquis (apixaban) starting around 2026 to 2028 depending on PTE outcomes, Opdivo (nivolumab) starting around 2026, Xarelto (rivaroxaban) with varying international timelines, Jardiance (empagliflozin) with U.S

Information Show FrequencyUpdated weekly Published28 October 2025 at 19:13 UTC Length30 min RatingClean