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In addition to a significant reduction in senescent cell burden within tissues treated with FOXO4-DRI, restoration of functional integrity was observed in organs such as the kidneys, liver, and skin

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The experimental procedures were conducted under a collaborative agreement between the Animal Production Research Station (Karada, Kafr El-Sheikh Governorate, Egypt) and the Faculty of Agriculture, Tanta University, and were approved by the latter (Approval No.: AY2019-2020/S6/2020.01.13/UPDATE 10/2025)

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