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Before this meta-analysis, the IM route was generally the preferred route, but our results showed that no route is usually preferred, and SL and oral routes should be considered comparable alternative routes

Energy blends land in the middle ground

The surface functionalisation of CQDs involves both covalent and non-covalent strategies to shape surface properties and functionalisation

This strategy suits users who achieved satisfactory improvements wanting to preserve results without full continuous intensity, willing to accept moderate benefit levels (70-85% of peak) rather than maximum continuous optimization, seeking to minimize costs while maintaining most improvements, and wanting simpler approach than complex cycling schedules