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Tirzepatide is a dual-action medication that activates both GLP-1 and GIP receptors, working through two hormonal pathways instead of just one

If side effects are troublesome, the SmPC advises that dose escalation can be delayed by an additional 4 weeks to allow better tolerance

Oscars host Jimmy Kimmel even joked about it on films night of nights last week

By addressing these broader factors, we can prevent obesity in the first place and make it easier to treat for those already affected." Specifically, Smith said that access to affordable whole foods that free from harmful additives, pesticides and dyes, was essential, and as was reversing the current food system's prioritization of "unhealthy, addictive ultra-processed foods." Other treatments also had a role to play, said Smith, including bariatric surgery which he said had been "shown to offer better long-term outcomes" than GLP-1 drugs