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This medication works by mimicking two naturally occurring incretin hormones that play crucial roles in glucose metabolism and appetite regulation
The study protocol was amended from version 1 to version 2 prior to enrollment of the first participant to add tirzepatide as an incretin mimetic therapy and to designate AEs of special interest (pancreatitis, liver injury, depression/suicidality and creatine kinase elevations)
Bloating is one of the most common side effects of GLP-1 injection treatments, including semaglutide (Wegovy) and tirzepatide (Mounjaro)
Staying well-hydrated supports overall digestive function, though individual responses to fluid intake with meals vary
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