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There have been a few rare cases of liver toxicity or autoimmune hepatitis in people taking curcumin preparations with piperine or black pepper for long periods

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Furthermore, a systematic review reported that erbium YAG lasers, fractional lasers, topical 5-FU, intramuscular injection of betamethasone, etc., improved the repigmentation effect as a combination therapy with narrow-band UVB55

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