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Random forest models to differentiate PD patients who were at the same or better Hoehn & Yahr (HY) stage in 2 years (the stable group) and who moved to the advanced HY stage in 2 years (the deteriorated group) using gut microbiota at year 0 revealed that the abundance of only two SCFA-producing genera, Fusicatenibacter and Faecalibacterium , at year 0 were able to predict the progression of PD patients at HY stage 1 in 2 years with an area-under-the-curve of receiver operating characteristics (AUROC) of 0.868 74

Patients without neuropathy weren't far behind, with increases from 32.1% to 78.3% [19]

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