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Synergy: Some women also pair it with an Akkermansia supplement for broader Akkermansia microbiome balance during menopause

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The pivotal programs are public, the STEP trials for semaglutide in weight management ( The New England Journal of Medicine , 2021), SURMOUNT for tirzepatide in weight management (NEJM, 2022), and SURMOUNT-OSA for tirzepatide in obstructive sleep apnea (NEJM, 2024)