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For example, an early study demonstrated that taking a 12-gram inositol supplement every day for 4 weeks improved symptoms in people with depression ( In contrast, subsequent studies were unable to show any significant benefits ( Overall, there is not enough evidence yet to say whether inositol has a true effect on depression

And there's a hormone that's released from there called melanocyte-stimulating hormone

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SIRT1, which is a histone deacetylase (HDAC), is abundantly expressed in renal tubules, participates in the regulation of kidney physiology and protects against renal fibrosis, oxidative damage, inflammation and apoptosis through the deacetylation of numerous transcription factors 48,49,50