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Other studies have identified that the metabolites of acetaminophen, p-aminophenol or AM404, can indirectly activate CB1 receptors by inhibiting cellular uptake of the endogenous CB1 receptor agonist anandamide [32,33]

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Glutaryl-CoA dehydrogenase (GCDH) deficiency is an inborn error of lysine and tryptophan metabolism that results in increased formation and excretion of glutaric acid (GA), 3-hydroxyglutaric acid (3-OH-GA), glutaconic acid and glutarylcarnitine [82]

poorly soluble in organic solvents Stereochemistry: L-configuration (biologically active stereoisomer) The molecular structure features a quaternary ammonium group with three methyl substituents, a hydroxyl group, and a carboxylate function creating a zwitterionic compound at physiological pH