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Despite the debated GLP-1R expression in islet alpha-cells, recent studies have provided evidence that GLP-1R agonists may mediate direct effects on alpha-cells via GLP-1R action

The key is to return to your regular weekly schedule afterward rather than making early dosing a habit

Also published in the New England Journal of Medicine in 2022, the SURMOUNT-1 trial demonstrated that tirzepatide at the 15 mg dose produced an average weight loss of 22.5% of body weight over 72 weeks approaching results typically seen with bariatric surgery (Jastreboff et al., 2022, PMID: 35658024)

This not only accelerates the healing process but also improves the quality of the healed tissue, reducing the risk of complications such as infections or delayed healing