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The kynurenine pathway and excitotoxicity Kynurenines influence dopaminergic, noradrenergic, cholinergic, GABAergic, and glutamatergic neurotransmission, meaning that fluctuations in their concentrations will disrupt the neuronal-glial network and critically affect mood

The black appearance is not due to dirt but a chemical reaction called oxidation, where melanin in the sebum reacts with oxygen in the air

Skipping meals to sidestep nausea can backfire by reducing calorie intake too sharply, which may slow metabolism or create nutrient deficiencies

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