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Phase 2 (NA-931, 13 weeks): Key characteristics: Lowest GI adverse event rates of any drug in this comparison by a wide margin 83% of all GI events classified as "insignificant" No clinically meaningful difference in GI events between NA-931 and placebo No muscle loss observed However, the study was only 13 weeks with 125 participants -- tolerability at higher doses and longer durations is unknown Side-by-Side Comparison# NR = not reported

Rapid weight loss can affect muscle and bone if exercise is not included

Tirzepatide, marketed as Mounjaro , has been hailed as a revolutionary treatment for type 2 diabetes and weight loss

This link has not been determined in humans, but Wegovy should not be taken by people with a personal or family history of thyroid tumours or a condition called MEN-2