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Stress Reporter Assay of AQ-QI and DEAQ-QI To identify the stress response pathways upon AQ-QI and DEAQ-QI exposure, oxidative stress response (SRXN1-GFP), ER stress response (CHOP-GFP), inflammation response (ICAM1-GFP), and DNA damage response (p21-GFP) pathways were measured with a high-content image-based BAC-GFP stress responses reporter assay (Wink et al., 2014, 2017)

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[Google Scholar] Arjinpathana N, Asawanonda P

They advise that patients with a family history of medullary thyroid carcinoma, a type of thyroid cancer, or those with Multiple Endocrine Neoplasia syndrome type 2 (MEN 2), should not use these medications