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And there is a countervailing consideration the frequency logic tends to omit: more frequent stimulation of the ghrelin receptor raises the theoretical prospect of desensitization over time, so more pulses per day is not straightforwardly more effect, even on the models own terms

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A submucosal collection of hemoglobin or hemosiderin, produced by extravasation and/or lysis of red blood cells, may impart a red, blue, or brown ephemeral appearance to the oral mucosa

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